Ocampo Sosa, Alain Antonio

Correo Electrónico: aocampo@idival.org

Grado: Doctor

ResearcherID: http://www.researcherid.com/rid/K-8261-2015

Unidades de Investigación:

ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLÍNICA

Stages in my professional career:
· 1995-1998: Researcher. Institute of Tropical Medicine "Pedro Kouri", Havana,
Cuba.
· 1998: Researcher. Nuclear Laser Medicine, s.r.l. Milano, Italy
· 1999-2004: Predoctoral researcher. University of cantabria.
· 2005-2007: Postdoctoral researcher. University of Bristol, UK
· 2007-2009: Postdoctoral researcher Marie Curie (TOK), NUIG, Ireland.
· 2010-2012. Postdoctoral researcher. Training and Research Institute Marquis of Valdecilla.
· 2013 to the present. Miguel Servet researcher. Marqués Research Institute of Valdecilla (IDIVAL).
In February 1999, after having been working as a researcher in the company italiana Nuclear Laser Medicine s.r.l in Milan, and previously at the Institute of Tropical Medicine "Pedro Kurí", in Havana, Cuba, I begin my doctoral thesis at the University of Cantabria.
The reason why I chose this center to train as a researcher was the subject of work, that attracted me powerfully: the molecular typing of the Brucella genus and the mechanism Molecular transposition of a specific insertion sequence of this genus, IS711.
At that time there was a need to improve identification procedures and typing of the Brucella genus, since conventional phenotypic methods were very cumbersome. During my PhD studies we were able to develop a rapid method of identification by means of a multipex (AMOS-ERY) that allowed to detect all the species of Brucella and differentiate biovars 3, 5, 6 and 9, from the rest, previously indistinguishable, likewise we could distinguish a new biovar 3b and determine the biological functionality of IS711 in strains of B. ovis and other species isolated from marine mammals. During my first stay postdoctoral at the University of Bristol, UK, I continued to develop identification methods and bacterial typing, but this time in Rhodococcus equi, a pathogen that affects mainly foals, and I participated in the sequencing of the genome of a pathogenic strain of said microorganism and of one of the virulence plasmids of R. equi, pVAPB1593. In my second postdoctoral stay I got a Marie Curie (TOK) scholarship, which I developed in the National University of Ireland in Galway, Ireland, primarily aimed at the study of the mechanisms of resistance to biocides and disinfectants in Pseudomonas aeruginosa and Salmonella enterica. Since 2010 I have been working on the study of mechanisms of resistance to antibiotics in gram negative bacteria of clinical interest such as P. aeruginosa, Burkholderia spp. Klebsiella pneumoniae and Acinetobacter baumannii, among others. Since 2013 I lead my own lines of research funded by the Fondo de Health Research (FIS). The objectives that focus my current research are the study of the mechanisms of resistance to carbapenems in P. aeruginosa, fundamentally mediated by the OprD porina, as well as its regulation and in the study of the systems of type VI secretion (T6SS) in P. aeruginosa and Burkholderia cepacia complex, focusing on the search for new effectors and their interaction with other bacteria and eukaryotic cells, the formation of biofilms and the relationship of these with antibiotic resistance

Fernandez-Manteca, Maria Gabriela, Garcia, Borja Garcia, Gomez-Galdos, Celia, Mirapeix, Jesus, Arniz-Mateos, Rosa, Garcia-Escarzaga, Asier, Gutierrez-Zugasti, Igor, Algorri, Jose Francisco, Lopez-Higuera, Jose Miguel, Ocampo-Sosa, Alain A., Rodriguez-Cobo, Luis, Cobo, Adolfo. Structural Pattern Analysis in Patella vulgata Shells Using Raman Imaging. APPL SCI-BASEL 15 -. 7 may 2025. . . F.I.:2,500 [doi:10.3390/app15095180]

Pablo-Marcos D, Fernández-Diego L, Rodríguez-Grande J, Fraile-Valcárcel N, Ortiz-Cartagena C, Pacios O, García-García S, García-Fernández S, Blasco L, Ocampo-Sosa A, Calvo-Montes J, Tomás M. «An accurate amplification-free CRISPR/Cas12a-based assay for GES ß-lactamase detection».. INT J ANTIMICROB AG 66 107506-107506. 3 abr 2025. 3 abr 2025. . F.I.:4,900 [doi:10.1016/j.ijantimicag.2025.107506]

Lara I, Hernandez-Ruiz V, Fernández-Huerta M, Rodriguez-Grande J, Arnaiz de Las Revillas F, Rodriguez-Lozano J, Calvo-Montes J, Ocampo-Sosa A, Fariñas MC, Roiz Mesones MP, Garcia-Fernandez S, Moure Z. Mycoplasma genitalium and antimicrobial resistance among the general female and male population in northern Spain.. SEX TRANSM INFECT -. 12 mar 2025. 12 mar 2025. . F.I.:3,600 [doi:10.1136/sextrans-2024-056374]

Hernandez, Marta, Falco-Prieto, Alvaro, Ugarte-Ruiz, Maria, Miguela-Villoldo, Pedro, Ocampo-Sosa, Alain, Abad, David, Perez-Sancho, Marta, Alvarez, Julio, Cadamuro, Rafael Dorighello, Elois, Mariana Alves, Fongaro, Gislaine, Quesada, Alberto, Gonzalez-Zorn, Bruno, Dominguez, Lucas, Eiros, Jose M, Rodriguez-Lazaro, David. Genome Analysis of 6222 Bacterial Isolates from Livestock and Food Environments in Spain to Decipher the Antibiotic Resistome.. ANTIBIOTICS-BASEL 14 -. 8 mar 2025. . . F.I.:4,300 [doi:10.3390/antibiotics14030281]

Fernández-Manteca MG, García BG, Álvarez SD, Gómez-Galdós C, Pérez-Asensio A, Algorri JF, Monteoliva AP, López-Higuera JM, Rodríguez-Cobo L, Ocampo-Sosa AA, Cobo A. Comprehensive Raman spectroscopy analysis for differentiating toxic cyanobacteria through multichannel 1D-CNNs and SHAP-based explainability.. TALANTA 292 127845-127845. 7 mar 2025. 7 mar 2025. . F.I.:5,600 [doi:10.1016/j.talanta.2025.127845]

Garcia Garcia, Borja, Fernandez-Manteca, Maria Gabriela, Gomez-Galdos, Celia, Deus Alvarez, Susana, Monteoliva, Agustin P, Lopez-Higuera, Jose Miguel, Algorri, Jose Francisco, Ocampo-Sosa, Alain A, Rodriguez-Cobo, Luis, Cobo, Adolfo. Integration of Fluorescence Spectroscopy into a Photobioreactor for the Monitoring of Cyanobacteria.. BIOSENSORS-BASEL 15 -. 20 feb 2025. . . F.I.:4,900 [doi:10.3390/bios15030128]

Fernández-Manteca MG, Ocampo-Sosa AA, Vecilla DF, Ruiz MS, Roiz MP, Madrazo F, Rodríguez-Grande J, Calvo-Montes J, Rodríguez-Cobo L, López-Higuera JM, Fariñas MC, Cobo A. Identification of hypermucoviscous Klebsiella pneumoniae K1, K2, K54 and K57 capsular serotypes by Raman spectroscopy.. SPECTROCHIM ACTA A 319 124533-124533. 15 oct 2024. 27 may 2024. . F.I.:4,300 [doi:10.1016/j.saa.2024.124533]